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1. WO2016086189 - HETERODIMERIC ANTIBODIES THAT BIND CD3 AND TUMOR ANTIGENS

Publication Number WO/2016/086189
Publication Date 02.06.2016
International Application No. PCT/US2015/062772
International Filing Date 25.11.2015
IPC
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 16/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C07K 16/30 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
C07K 16/46 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 16/2809
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2809against the T-cell receptor (TcR)-CD3 complex
C07K 16/2818
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2818against CD28 or CD152
C07K 16/2896
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2896against molecules with a "CD"-designation, not provided for elsewhere
C07K 16/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
Applicants
  • XENCOR, INC. [US]/[US]
Inventors
  • MOORE, Gregory
  • DESJARLAIS, John
  • BERNETT, Matthew
  • CHU, Seung
  • RASHID, Rumana
  • MUCHHAL, Umesh
  • LEE, Sung-Hyung
Agents
  • MACDOUGALL, Chirstina, A.
Priority Data
62/084,90826.11.2014US
62/085,02726.11.2014US
62/085,10626.11.2014US
62/085,11726.11.2014US
62/159,11108.05.2015US
62/250,97104.11.2015US
62/251,00504.11.2015US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) HETERODIMERIC ANTIBODIES THAT BIND CD3 AND TUMOR ANTIGENS
(FR) ANTICORPS HÉTÉRODIMÉRIQUES SE LIANT À L'ANTIGÈNE CD3 ET À UN ANTIGÈNE TUMORAL
Abstract
(EN) The present invention is directed to novel heterodimeric antibodies.
(FR) La présente invention porte sur de nouveaux anticorps hétérodimériques.
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