Processing

Please wait...

Settings

Settings

Goto Application

1. WO2011060389 - SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS

Publication Number WO/2011/060389
Publication Date 19.05.2011
International Application No. PCT/US2010/056757
International Filing Date 15.11.2010
IPC
A01N 43/82 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
72having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms
82five-membered rings with three hetero atoms
A61K 31/41 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
CPC
A61K 2300/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2300Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
A61K 31/4245
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
4245Oxadiazoles
A61K 31/454
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
445Non condensed piperidines, e.g. piperocaine
4523containing further heterocyclic ring systems
454containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/5377
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
53751,4-Oxazines, e.g. morpholine
5377not condensed and containing further heterocyclic rings, e.g. timolol
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
Applicants
  • RECEPTOS, INC. [US]/[US] (AllExceptUS)
  • MARTINBOROUGH, Esther [US]/[US] (UsOnly)
  • BOEHM, Marcus, F. [US]/[US] (UsOnly)
  • YEAGER, Adam, Richard [US]/[US] (UsOnly)
  • TAMIYA, Junko [JP]/[US] (UsOnly)
  • HUANG, Liming (UsOnly)
  • BRAHMACHARY, Enugurthi (UsOnly)
  • MOORJANI, Manisha (UsOnly)
Inventors
  • MARTINBOROUGH, Esther
  • BOEHM, Marcus, F.
  • YEAGER, Adam, Richard
  • TAMIYA, Junko
  • HUANG, Liming
  • BRAHMACHARY, Enugurthi
  • MOORJANI, Manisha
Agents
  • BLAYLOCK, Richard, L.
Priority Data
61/261,28213.11.2009US
61/262,47418.11.2009US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS
(FR) MODULATEURS DU RÉCEPTEUR DE SPHINGOSINE-1-PHOSPHATE ET PROCÉDÉS DE SYNTHÈSE CHIRALE
Abstract
(EN) Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the SlP receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.
(FR) L'invention concerne des composés destinés à moduler de façon sélective le récepteur de sphingosine-1-phosphate, notamment des composés qui modulent le sous-type 1 du récepteur S1P. L'invention concerne également des procédés de synthèse chirale de ces composés. L'invention concerne encore des utilisations, des méthodes de traitement ou de prévention, ainsi que des procédés de préparation de compositions contenant les composés selon l'invention, contribuant au traitement ou à la prévention de maladies, d'affections et de troubles contre lesquels la modulation du récepteur de sphingosine-1-phosphate est indiquée médicalement.
Latest bibliographic data on file with the International Bureau