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1. (WO2012153193) PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/153193 International Application No.: PCT/IB2012/001065
Publication Date: 15.11.2012 International Filing Date: 08.05.2012
IPC:
A61K 39/395 (2006.01) ,A61K 48/00 (2006.01) ,A61K 47/48 (2006.01) ,A61K 31/70 (2006.01) ,A61P 35/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
LEGOCHEM BIOSCIENCES, INC. [KR/KR]; Daejeon Bioventure Town 3F 461-8 Jeonmin-dong, Yuseong-gu Daejeon 305-811, KR (AllExceptUS)
KIM, Yongzu [KR/KR]; KR (UsOnly)
PARK, Taekyo [KR/KR]; KR (UsOnly)
WOO, Sungho [KR/KR]; KR (UsOnly)
LEE, Hyangsook [KR/KR]; KR (UsOnly)
KIM, Youngun [KR/KR]; KR (UsOnly)
CHO, Jongun [KR/KR]; KR (UsOnly)
JUNG, Doohwan [KR/KR]; KR (UsOnly)
KIM, Sunyoung [KR/KR]; KR (UsOnly)
KWON, Hyunjin [KR/KR]; KR (UsOnly)
OH, Kyuman [KR/KR]; KR (UsOnly)
CHUNG, Yunseo [KR/KR]; KR (UsOnly)
PARK, Yun-hee [KR/KR]; KR (UsOnly)
Inventors:
KIM, Yongzu; KR
PARK, Taekyo; KR
WOO, Sungho; KR
LEE, Hyangsook; KR
KIM, Youngun; KR
CHO, Jongun; KR
JUNG, Doohwan; KR
KIM, Sunyoung; KR
KWON, Hyunjin; KR
OH, Kyuman; KR
CHUNG, Yunseo; KR
PARK, Yun-hee; KR
Agent:
KIM, Moon Jae; Nam & Nam World Patent & Law Firm Kal Bldg. 3rd Fl. 41-3, Seosomun-Dong, Jung-Gu Seoul 100-813, KR
Priority Data:
61/483,69808.05.2011US
Title (EN) PROTEIN-ACTIVE AGENT CONJUGATES AND METHOD FOR PREPARING THE SAME
(FR) CONJUGUÉS PROTÉINE-PRINCIPE ACTIF ET LEUR PROCÉDÉ DE PRÉPARATION
Abstract:
(EN) The invention provides protein- active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates, as well as methods for making the conjugates and compositions. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent).
(FR) L'invention concerne des conjugués protéine-principe actif ayant un motif acide aminé qui peut être reconnu par une isoprénoïde transférase. L'invention concerne également des compositions contenant les conjugués, ainsi que des procédés de fabrication des conjugués et des compositions. L'invention concerne en outre des procédés d'utilisation des conjugués pour administrer le principe actif à une cellule cible, ainsi que des procédés d'utilisation des conjugués pour traiter un sujet en ayant besoin (par exemple un sujet ayant besoin du principe actif).
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA2835576EP2707031CN103648530KR1020140035393SG194875JP2014519492
MX2013013069RU2013154264BR112013028907RU0002613906MYPI 2013004045PH1/2013/502284
JP2017206515IN9435/CHENP/2013