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1. WO2010052014 - TREATMENT OF ACUTE LYMPHOBLASTIC LEUKEMIA

Publication Number WO/2010/052014
Publication Date 14.05.2010
International Application No. PCT/EP2009/007970
International Filing Date 06.11.2009
IPC
C07K 16/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C07K 16/46 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
C07K 16/2803
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
C07K 16/2809
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2809against the T-cell receptor (TcR)-CD3 complex
C07K 16/468
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
C07K 2317/31
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
30characterized by aspects of specificity or valency
31multispecific
Applicants
  • MICROMET AG [DE]/[DE] (AllExceptUS)
  • ZUGMAIER, Gerhard [DE]/[DE] (UsOnly)
  • DEGENHARD, Evelyn [AT]/[DE] (UsOnly)
Inventors
  • ZUGMAIER, Gerhard
  • DEGENHARD, Evelyn
Agents
  • Vossius & Partner
Priority Data
61/112,32307.11.2008US
61/183,29102.06.2009US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TREATMENT OF ACUTE LYMPHOBLASTIC LEUKEMIA
(FR) TRAITEMENT DE LA LEUCÉMIE LYMPHOBLASTIQUE AIGUË
Abstract
(EN) The present invention relates to a method for the treatment, amelioration or elimination of acute lymphoblastic leukemia (ALL), the method comprising the administration of a pharmaceutical composition comprising a CD19xCD3 bispecific single chain antibody construct to an adult patient in the need thereof.
(FR) Cette invention concerne une méthode permettant de traiter, d'améliorer ou de guérir une leucémie lymphoblastique aiguë (LLA) consistant à administrer une composition pharmaceutique contenant une construction d'anticorps bispécifique à chaîne unique CD19xCD3 à un patient adulte atteint de LLA qui en a besoin.
Related patent documents
RU2011122819This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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