WO2008068230 ANAPLEROTIC THERAPY OF HUNTINGTON DISEASE AND OTHER POLYGLUTAMINE DISEASES

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Publication Number WO/2008/068230

Publication Date 12.06.2008

International Application No. PCT/EP2007/063181

International Filing Date 03.12.2007

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Applicants

INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) [FR]/[FR] (AllExceptUS)
DÜRR, Alexandra [FR]/[FR] (UsOnly)
MOCHEL, Fanny [FR]/[FR] (UsOnly)

Inventors

DÜRR, Alexandra
MOCHEL, Fanny

Agents

CABINET PLASSERAUD

Priority Data

06291873.5

04.12.2006

Publication Language English (en)

Filing Language English (EN)

Designated States

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Title

(EN) ANAPLEROTIC THERAPY OF HUNTINGTON DISEASE AND OTHER POLYGLUTAMINE DISEASES

(FR) THÉRAPIE ANAPLÉROTIQUE DE LA MALADIE DE HUNTINGTON ET D'AUTRES MALADIES LIÉES À LA POLYGLUTAMINE

Abstract

(EN) The present invention relates to a method for treating and/or preventing Huntington disease and other polyglutamine diseases, comprising the step of administering an effective amount of a precursor of propionyl-CoA to an individual in need thereof.

(FR) La présente invention concerne un procédé de traitement et/ou de prévention de la maladie de Huntington et d'autres maladies liées à la polyglutamine, ledit procédé comprenant l'étape d'administration d'une quantité efficace d'un précurseur du propionyle-CoA à un individu qui en a besoin.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1	Foods or foodstuffs; Their preparation or treatment
03	containing additives

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1	Foods or foodstuffs; Their preparation or treatment
29	Modifying nutritive qualities of foods; Dietetic products
30	containing additives

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1	Foods or foodstuffs; Their preparation or treatment
03	containing additives

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1. WO2008068230 - ANAPLEROTIC THERAPY OF HUNTINGTON DISEASE AND OTHER POLYGLUTAMINE DISEASES

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
29	Foods or foodstuffs containing additives
03	Organic compounds
035	containing oxygen as heteroatom
04	Fatty acids or derivatives

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
V	INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2002	Food compositions, function of food ingredients or processes for food or foodstuffs

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25	Drugs for disorders of the nervous system
28	for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia