WO2005055993 PHARMACEUTICAL PREPARATION CONTAINING GABAPENTIN

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Publication Number WO/2005/055993

Publication Date 23.06.2005

International Application No. PCT/EP2004/053233

International Filing Date 02.12.2004

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Applicants

ZAMBON GROUP S.P.A. [IT]/[IT] (AllExceptUS)
RAMPOLDI, Luca [IT]/[IT] (UsOnly)
GRASSANO, Alessandro [IT]/[IT] (UsOnly)

Inventors

RAMPOLDI, Luca
GRASSANO, Alessandro

Agents

LONGONI, Alessandra

Priority Data

MI2003A002399

09.12.2003

Publication Language English (en)

Filing Language English (EN)

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Title

(EN) PHARMACEUTICAL PREPARATION CONTAINING GABAPENTIN

(FR) PREPARATION PHARMACEUTIQUE COMPRENANT DE LA GABAPENTINE

Abstract

(EN) A gabapentin granulate obtained by granulating gabapentin with PEG having a melting point comprised between 50 and 80°C and pharmaceutical compositions containing it, are described.

(FR) L'invention concerne un granulé de gabapentine obtenu par granulation de la gabapentine avec PEG possédant un point de fusion compris entre 50 et 80 °C et des compostions pharmaceutiques renfermant celui-ci.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders
16	Agglomerates; Granulates; Microbeadlets

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
20	Pills, lozenges or tablets

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25	Drugs for disorders of the nervous system
08	Antiepileptics; Anticonvulsants

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders
16	Agglomerates; Granulates; Microbeadlets

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
20	Pills, lozenges or tablets

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1. WO2005055993 - PHARMACEUTICAL PREPARATION CONTAINING GABAPENTIN

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
185	Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19	Carboxylic acids, e.g. valproic acid
195	having an amino group

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16	Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1605	Excipients; Inactive ingredients
1629	Organic macromolecular compounds
1641	obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
20	Pills, tablets, ; discs, rods
2072	characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
2077	Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
185	Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19	Carboxylic acids, e.g. valproic acid
195	having an amino group