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1. NZ785977 - HPK1 ANTAGONISTS AND USES THEREOF

Office
New Zealand
Application Number 785977
Application Date 09.03.2022
Publication Number 785977
Publication Date 25.03.2022
Publication Kind A
IPC
A61K 31/4035
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
4035Isoindoles, e.g. phthalimide
C07D 209/44
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
44Iso-indoles; Hydrogenated iso-indoles
A61P 35/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
04specific for metastasis
Applicants Nimbus Saturn, Inc.
Inventors KAILA, Neelu
LINNEY, Ian
WARD, Stuart
WISHART, Grant
WHITTAKER, Ben
COTE, Alexandre
GREENWOOD, Jeremy Robert
LEFFLER, Abba
SEVERANCE, Daniel L.
ALBANESE, Steven K.
Agents Spruson & Ferguson Pty Ltd
Priority Data 62/900,152 13.09.2019 US
63/032,070 29.05.2020 US
Title
(EN) HPK1 ANTAGONISTS AND USES THEREOF
Abstract
(EN) The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.
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