NZ777721 Oxysterols and methods of use thereof

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Application Number 777721

Application Date 06.07.2016

Publication Number 777721

Publication Date 29.06.2021

Publication Kind A

IPC

Applicants SAGE THERAPEUTICS, INC.

Inventors SALITURO, Francesco, G.
MARTINEZ BOTELLA, Gabriel
HARRISON, Boyd, L.
ROBICHAUD, Albert, Jean

Agents Spruson & Ferguson Pty Ltd

Priority Data 62/189,068 06.07.2015 US
62/332,931 06.05.2016 US

Title

(EN) Oxysterols and methods of use thereof

Abstract

(EN) Compounds are provided according to Formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, and R3are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
56	Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565	not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
567	substituted in position 17 alpha, e.g. mestranol, norethandrolone

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
56	Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565	not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
566	having an oxo group in position 17, e.g. oestrone

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
56	Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565	not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
567	substituted in position 17 alpha, e.g. mestranol, norethandrolone

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
56	Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565	not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
566	having an oxo group in position 17, e.g. oestrone

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1. NZ777721 - Oxysterols and methods of use thereof