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1. NZ743621 - BOTANICAL COMPOSITIONS OF SALVIA OFFICINALIS WITH ACTIVITY IN EXTENDING CHRONOLOGICAL LIFESPAN AND METHODS OF USE

Office
New Zealand
Application Number 743621
Application Date 21.06.2018
Publication Number 743621
Publication Date 29.06.2018
Publication Kind A
IPC
A61K 36/537
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
537Salvia (sage)
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants SIBELIUS LIMITED
Inventors LEYLAND, Peter Anthony
AKOULITCHEV, Alexandre
VERSLYPE, Antoine
CAIGER, Stephen
Agents JAMES & WELLS
Priority Data 1601520.8 27.01.2016 GB
Title
(EN) BOTANICAL COMPOSITIONS OF SALVIA OFFICINALIS WITH ACTIVITY IN EXTENDING CHRONOLOGICAL LIFESPAN AND METHODS OF USE
Abstract
(EN) Compositions comprising a nutritionally or pharmaceutically effective dosage of an extract of Salvia officinalisand an acceptable carrier are provided. The compositions show particular potential in the treatment of age-related pathologies in humans or animals. The extracts are obtained from varieties and cultivars of Salvia officinalisthat possess a unique chemical fingerprint that includes unusually low thujone content in the leaf. When tested in C. elegansscreening assays compositions that comprise the extract elicit an increase in mean chronological lifespan (CLS)in theC. eleganspopulation of at least 10%.