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1. MYPI 2015702302 - MICROORGANISM FOR PRODUCTION OF CHEMICALS DERIVED FROM ACETYL-COA

Office
Malaysia
Application Number PI 2015702302
Application Date 23.01.2014
Publication Number PI 2015702302
Publication Date 24.07.2014
Publication Kind A
IPC
C
CCHEMISTRY; METALLURGY
C
CCHEMISTRY; METALLURGY
C
CCHEMISTRY; METALLURGY
Applicants MITSUI CHEMICALS, INC
Inventors CHONG, SU SUN
HIDESAKI, Tomonori
FUJII, Ryota
MADHAVAN, Anjali
Agents PATRICK MIRANDAH
Priority Data 2013-011535 24.01.2013 JP
Title
(EN) MICROORGANISM FOR PRODUCTION OF CHEMICALS DERIVED FROM ACETYL-COA
Abstract
(EN) Disclosed is an acetyl-CoA-producing microorganism, which is obtained by imparting malate thiokinase and malyl-CoA lyase enzymatic activities to a microorganism having none of the following (a), (b), (c) or (d), without imparting any of (a), (b), (c) or (d), or, even when one or more of (a), (b), (c) or (d) are imparted, not allowing the functions thereof to be exerted: (a) a carbon dioxide fixation cycle having an enzymatic reaction from malonyl-CoA to malonate semialdehyde or 3-hydroxypropionate, (b) a carbon dioxide fixation cycle having an enzymatic reaction from acetyl-CoA and CO2 to pyruvate, (c) a carbon dioxide fixation cycle having an enzymatic reaction from crotonyl� CoA and CO2 to ethylmalonyl-CoA or glutaconyl-CoA or (d) a carbon dioxide fixation cycle having an enzymatic reaction from CO2 to formate.