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1. MYPI 2010001528 - 2'-FLUORO-2'DEOXYTETRAHYDROURIDINES AS CYTIDINE DEAMINASE INHIBITORS

Office
Malaysia
Application Number PI 2010001528
Application Date 16.10.2008
Publication Number PI 2010001528
Publication Date 25.04.2013
Publication Kind A
IPC
A61K 31/706
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07H 19/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
Applicants OTSUKA PHARMACEUTICAL CO., LTD.
Inventors LAPIDUS, RENA
DUVALL, BRIDGET
FERRARIS, DANA V.
TSUKAMOTO, TAKASHI
HAMILTON, GREGORY S.
Agents OON YEN YEN*
Priority Data 60/980,397 16.10.2007 US
Title
(EN) 2'-FLUORO-2'DEOXYTETRAHYDROURIDINES AS CYTIDINE DEAMINASE INHIBITORS
Abstract
(EN) THE PRESENT INVENTION PROVIDES CERTAIN TETRAHYDROURIDINE DERIVATIVE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND METHODS OF MAKING AND USING SUCH COMPOUNDS.
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