MXPA/a/1992/004546 PROCESO PARA LA PREPARACION DE NATAMICINA PORFERMENTACION

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Mexico

Application Number PA/a/1992/004546

Application Date 05.08.1992

Publication Number PA/a/1992/004546

Publication Date 06.05.1993

Publication Kind A

IPC

Applicants BIO-TECHNICAL RESOURCES

Inventors PHILLIP TERRY OLSON
MICHAEL ALLEN EISENSCHINK
JAMES R. MILLIS

Agents BERNARDO GOMEZ VEGA

Priority Data 740,545 05.08.1991 US

Title

(ES) PROCESO PARA LA PREPARACION DE NATAMICINA PORFERMENTACION

Abstract

(ES) La presente invención se refiere a un proceso para preparar natamicina por fermentación, caracterizado porque:a) el inóculo comprende de un cultivo de Streptomyces productor de natamicina y un medio que comprende nitrógeno proteico y una fuente de carbono metabolizable, en exceso de aquella requerida para evitar el agotamiento de carbono durante la propagación del inóculo;y b) el medio de producción de natamicina comprende de 80 a 250 g/l de una fuente de carbono metabolizable y 15 a 80 g/l de una fuente de nitrógeno proteico.

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1	Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20	Bacteria; Culture media therefor

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
R	INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C-C12Q75
1	Microorganisms
01	Bacteria or actinomycetales
465	Streptomyces

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N	MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1	Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20	Bacteria; Culture media therefor

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P	FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19	Preparation of compounds containing saccharide radicals
44	Preparation of O-glycosides, e.g. glucosides
60	having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
62	the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

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1. MXPA/a/1992/004546 - PROCESO PARA LA PREPARACION DE NATAMICINA PORFERMENTACION