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1. MXMX/a/2008/016533 - GALENICAL FORMULATIONS OF ALISKIREN AND HYDROCHLOROTHIAZIDE

Office Mexico
Application Number MX/a/2008/016533
Application Date 19.12.2008
Publication Number MX/a/2008/016533
Publication Date 12.05.2009
Publication Kind A
IPC
A61K 31/165
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
A61K 31/549
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
54having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame
549having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
A61K 9/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
Applicants NOVARTIS AG.*
Inventors Matthias Willmann
Agents CESAR RAMOS DE MIGUEL*
Priority Data 0612540.5 23.06.2006 GB
Title
(EN) GALENICAL FORMULATIONS OF ALISKIREN AND HYDROCHLOROTHIAZIDE
(ES) FORMULACIONES GALENICAS DE ALISQUIRENO E HIDROCLOROTIAZIDA
Abstract
(EN)
The present invention relates to a solid oral dosage form comprising a therapeutically effective amount of aliskiren or a pharmaceutically acceptable salt thereof, a therapeutically effective amount of HCTZ and a hydrophilic filler selected from the group a carbohydrate or combinations thereof, e.g. sugars, sugar alcohols and starches or combinations of these.

(ES)
La presente invención se refiere a una forma de dosificación oral sólida, la cual comprende una cantidad terapéuticamente efectiva de alisquireno, o una sal farmacéuticamente aceptable del mismo, una cantidad terapéuticamente efectiva de hidroclorotiazida, y un relleno hidrofílico seleccionado a partir del grupo de un carbohidrato o combinaciones del mismo, por ejemplo azúcares, alcoholes de azúcar, y almidones, o combinaciones de los mismos.