MX2019014436 DERIVADOS DE PIRIDOQUINAZOLINA EFICACES COMO INHIBIDORES DE PROTEINA QUINASA.

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Mexico

Application Number 2019014436

Application Date 29.11.2019

Publication Number 2019014436

Publication Date 10.02.2020

Publication Kind A

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Applicants ONCOSTELLAE, S.L.

Inventors Guido KURZ
Juan CAMACHO GÓMEZ

Priority Data 201730759 23.06.2017 ES

Title

(EN) DERIVADOS DE PIRIDOQUINAZOLINA EFICACES COMO INHIBIDORES DE PROTEINA QUINASA.

(ES) DERIVADOS DE PIRIDOQUINAZOLINA EFICACES COMO INHIBIDORES DE PROTEINA QUINASA.

Abstract

(EN) The present invention relates to novel 11-oxo-11H-pyrido[2,1 b]quinazoline-6-carboxamide derivatives of formula (I) as potent inhibitors of protein kinase, to pharmaceutical compositions containing them and to the use of said compounds for the manufacture of a drug for the treatment of diseases or pathological diseases that can be improved by inhibiting protein kinase.

(ES) La presente invención se refiere a nuevos derivados de 11-oxo-11H-pirido [2,1-b] quinazolina-6-carboxamida como potentes inhibidores de proteína quinasa, a composiciones farmacéuticas que los contienen y al uso de dichos compuestos para la fabricación de un medicamento para el tratamiento de afecciones o enfermedades patológicas que pueden mejorar mediante la inhibición de proteína quinasa.

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
471	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
471	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17	Drugs for dermatological disorders
06	Antipsoriatics

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
471	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

F	MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
24	HEATING; RANGES; VENTILATING
C	DOMESTIC STOVES OR RANGES
7	Stoves or ranges heated by electric energy
08	Arrangement or mounting of control or safety devices
082	on ranges, e.g. control panels, illumination

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1. MX2019014436 - DERIVADOS DE PIRIDOQUINAZOLINA EFICACES COMO INHIBIDORES DE PROTEINA QUINASA.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495	having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505	Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519	ortho- or peri-condensed with heterocyclic rings