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1. MX2019014436 - DERIVADOS DE PIRIDOQUINAZOLINA EFICACES COMO INHIBIDORES DE PROTEINA QUINASA.

Office
Mexico
Application Number 2019014436
Application Date 29.11.2019
Publication Number 2019014436
Publication Date 10.02.2020
Publication Kind A
IPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
A61P 17/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
06Antipsoriatics
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
F24C 7/082
FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
24HEATING; RANGES; VENTILATING
CDOMESTIC STOVES OR RANGES 
7Stoves or ranges heated by electric energy
08Arrangement or mounting of control or safety devices
082on ranges, e.g. control panels, illumination
F24C 7/087
FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
24HEATING; RANGES; VENTILATING
CDOMESTIC STOVES OR RANGES 
7Stoves or ranges heated by electric energy
08Arrangement or mounting of control or safety devices
087of electric circuits regulating heat
A61K 31/519
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants ONCOSTELLAE, S.L.
Inventors Guido KURZ
Juan CAMACHO GÓMEZ
Priority Data 201730759 23.06.2017 ES
Title
(EN) DERIVADOS DE PIRIDOQUINAZOLINA EFICACES COMO INHIBIDORES DE PROTEINA QUINASA.
(ES) DERIVADOS DE PIRIDOQUINAZOLINA EFICACES COMO INHIBIDORES DE PROTEINA QUINASA.
Abstract
(EN) The present invention relates to novel 11-oxo-11H-pyrido[2,1 b]quinazoline-6-carboxamide derivatives of formula (I) as potent inhibitors of protein kinase, to pharmaceutical compositions containing them and to the use of said compounds for the manufacture of a drug for the treatment of diseases or pathological diseases that can be improved by inhibiting protein kinase.
(ES) La presente invención se refiere a nuevos derivados de 11-oxo-11H-pirido [2,1-b] quinazolina-6-carboxamida como potentes inhibidores de proteína quinasa, a composiciones farmacéuticas que los contienen y al uso de dichos compuestos para la fabricación de un medicamento para el tratamiento de afecciones o enfermedades patológicas que pueden mejorar mediante la inhibición de proteína quinasa.