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1. MX367268 - NUEVAS COMPOSICIONES DE VACUNA QUE COMPRENDEN OLIGONUCLEOTIDOS INMUNOESTIMULANTES.

Office
Mexico
Application Number 2015015758
Application Date 13.11.2015
Publication Number 367268
Publication Date 16.03.2016
Grant Number 367268
Grant Date 12.08.2019
Publication Kind B
IPC
A61K 39/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
002Protozoa antigens
008Leishmania antigens
CPC
A61K 39/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
002Protozoa antigens
008Leishmania antigens
A61K 39/27
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
27Equine rhinopneumonitis virus
A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 2039/55561
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55561CpG containing adjuvants; Oligonucleotide containing adjuvants
A61K 2039/55577
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55577Saponins; Quil A; QS21; ISCOMS
C12N 2710/16034
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2710dsDNA Viruses
00011dsDNA Viruses
16011Herpesviridae
16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applicants ZOETIS SERVICES LLC
Inventors DOMINOWSKI, Paul Joseph
KREBS, Richard Lee
RAI, Sharath K.
SLY, Laurel Mary
COOK, Corey Patrick
MWANGI, Duncan
FOSS, Dennis L.
Priority Data 61/823,189 14.05.2013 US
Title
(EN) NUEVAS COMPOSICIONES DE VACUNA QUE COMPRENDEN OLIGONUCLEOTIDOS INMUNOESTIMULANTES.
(ES) NUEVAS COMPOSICIONES DE VACUNA QUE COMPRENDEN OLIGONUCLEOTIDOS INMUNOESTIMULANTES.
Abstract
(EN) The invention provides a vaccine composition comprising an antigen component and an adjuvant component, wherein the adjuvant component comprises a P-class immunostimulatory oligonucleotide and either a combination of a saponin and a sterol; or an oily phase comprising an oil and, optionally, one or more emulsifiers, said oily phase comprising 2-20% v/v of the vaccine composition, wherein said antigen component is an EHV antigen or a Leishmania antigen.
(ES) La presente invención se refiere a una composición de vacuna que comprende un componente de antígeno y un componente de adyuvante, en la que el componente de adyuvante comprende un oligonucleótido inmunoestimulante de clase P y o bien una combinación de una saponina y un esterol; o una fase oleosa que comprende un aceite y, opcionalmente, uno o más emulsionantes, comprendiendo dicha fase oleosa el 2-20 % v / v de la composición de vacuna, en la que dicho componente de antígeno es un antígeno del EHV o un antígeno de Leishmania.