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1. (MXMX/a/2008/000367) 5,6-DI-SUBSTITUTED OXADIAZOLOPYRAZINES AND THIADIAZOLOPYRAZINES AS CXC-CHEMOKINE RECEPTOR LIGANDS

Office : Mexico
Application Number: MX/a/2008/000367 Application Date: 07.01.2008
Publication Number: MX/a/2008/000367 Publication Date: 27.06.2008
Publication Kind : A
Prior PCT appl.: Application Number:US2006024908 ; Publication Number:07005403 Click to see the data
IPC:
A61K 31/41
A61P 11/06
A61P 29/00
A61P 35/00
C07D 498/04
C07D 513/04
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
498
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
513
Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/, C07D477/232
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants: SCHERING CORPORATION.*
Inventors: PURAKKATTLE, Biju J.
Agents: FERNANDO ROSALES VAZQUEZ.*
Priority Data: 60/695,162 29.06.2005 US
Title: (EN) 5,6-DI-SUBSTITUTED OXADIAZOLOPYRAZINES AND THIADIAZOLOPYRAZINES AS CXC-CHEMOKINE RECEPTOR LIGANDS
(ES) OXIDIAZOLOPIRAZINAS Y TIADIAZOLOPIRAZINAS 5,6-DI-SUSTITUIDAS COMO LIGANDOS DE RECEPTOR DE QUIMIOCINA EN LA QUE DOS CISTERNAS SON SEPARADAS POR UN SOLO AMINOACIDO
Abstract:
(EN) Disclosed are compounds of the formula Chemical formula should be inserted here as it appears on the abstract in paper form. and the pharmaceutically acceptable salts thereof. The compounds are useful for the treatment of chemokine-mediated diseases such as COPD.
(ES) Se describen compuestos de la fórmula (ver fórmula (1.0)) y las sales farmacéuticamente aceptables de los mismos;los compuestos sonútiles para el tratamiento de enfermedades mediadas por quimiocina tales como COPD.
Also published as:
EP1907399JP2009500328ES2353401CN101253180CA2613428WO/2007/005403