Processing

Please wait...

Settings

Settings

1. MXMX/a/2007/016238 - PROLONGED RELEASE FORMULATION OF ACTIVE PRINCIPLES HAVING A PH-DEPENDENT SOLUBILITY

Office Mexico
Application Number MX/a/2007/016238
Application Date 17.12.2007
Publication Number MX/a/2007/016238
Publication Date 27.06.2008
Publication Kind A
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
12
Carboxylic acids; Salts or anhydrides thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
24
Layered or laminated unitary dosage forms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
28
Dragees; Coated pills or tablets
30
Organic coatings
36
containing carbohydrates or derivatives thereof
A61K 31/437
A61K 47/12
A61K 9/24
A61K 9/36
Applicants SANOFI-AVENTIS
Inventors Frédéric Andre
Gareth Lewis
Gerard Alaux
Véronique Serre
Agents CESAR RAMOS DE MIGUEL*
Priority Data 0506539 28.06.2005 FR
Title
(EN) PROLONGED RELEASE FORMULATION OF ACTIVE PRINCIPLES HAVING A PH-DEPENDENT SOLUBILITY
(ES) FORMULACION DE LIBERACION PROLONGADA DE PRINCIPIOS ACTIVOS QUE PRESENTAN UNASOLUBILIDAD DEPENDIENTE DE PH
Abstract
(EN)
The invention concerns a novel formulation for prolonged release of an active principle having a pH-dependent solubility. The inventive formulation comprises a matrix support based on hydrophilic polymer containing a specific dose of active principle, and further comprises on or more acidifying agents in the form of an acid salt of an organic acid.

(ES)
La invención se refiere a una nueva formulación para liberación prolongada de un principio activo que presenta una solubilidad dependiente de pH. La formulación de la invención comprende un excipiente matricial basado en polímero hidrofílico que contiene una dosis específica de principio activo, y además comprende uno o más agentes acidificantes en la forma de una salácido de unácido orgánico.