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1. MXMX/a/2007/002609 - PURIFICATION OF MONTELUKAST

Office Mexico
Application Number MX/a/2007/002609
Application Date 01.03.2007
Publication Number MX/a/2007/002609
Publication Date 03.10.2008
Publication Kind A
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
215
Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
02
having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
16
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
18
Halogen atoms or nitro radicals
C07D 215/18
Applicants TEVA PHARMACEUTICAL INDUSTRIES LTD.
Inventors Evgeny Shapiro
Greta Sterimbaum
Kobi Chen
Agents JULIAN VADILLO GONZALEZ.*
Priority Data 60/697,000 05.07.2005 US
Title
(EN) PURIFICATION OF MONTELUKAST
(ES) PURIFICACION DE MONTELUKAST
Abstract
(EN)
The present invention provides methods of purifying montelukast, a new isolated impurity of montelukast of formula I, method for its isolation, and method of using montelukast impurity as a reference marker and a reference standard.

(ES)
La presente invención proporciona métodos para purificar montelukast, una nueva impureza aislada de montelukast de la fórmula I, un método para su aislamiento, y método para utilizar impureza de montelukast como marcador de referencia y un parámetro de referencia.