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1. MXPA/a/2004/012271 - NEW QUINUCLIDINE AMIDE DERIVATIVES

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Office Mexico
Application Number PA/a/2004/012271
Application Date 07.12.2004
Publication Number PA/a/2004/012271
Publication Date 13.06.2005
Publication Kind A
IPC
A61K 31/407
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
407condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A61K 31/439
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
439the ring forming part of a bridged ring system, e.g. quinuclidine
A61P 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 13/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
C07D 209/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
Applicants LABORATORIOS ALMIRALL, S.A.
Inventors MARIA PRAT QUINONES
Agents CARLOS M. TRUJILLO C.
Priority Data 200201539 02.07.2002 ES
Title
(EN) NEW QUINUCLIDINE AMIDE DERIVATIVES
(ES) NUEVOS DERIVADOS DE QUINUCLIDINA-AMIDA
Abstract
(EN)
New quinuclidine amide derivatives having the chemical structure of general formula (I) and pharmaceutically acceptable salts thereof including quaternary salts of formula (II) are disclosed;as well as processes for their preparation, pharmaceutical compositions 10 comprising them and their use in therapy as antagonists of M3 muscarinic receptors.

(ES)
Nuevos derivados de quinuclidina-amida que tienen la estructura química de fórmula general (I)(ver fórmula I)y sales farmacéuticamente aceptables de los mismos, incluyendo las sales cuaternarias de fórmula (II)(ver fórmula II)asícomo procedimientos para su preparación, las composiciones farmacéuticas que los contiene y su uso en terapia como antagonistas de receptores muscarínicosMP3.
Also published as
AR040351
AU2003242757
CA2492535
CN1678610
EP1519933
ES2204295
ID042.191
IL165923
IN4140/DELNP/2004
JP2005533826
KR1020050024450
MYPI 20032447
NO20050164
NZ537341
PH1-2004-502126
RU02314306
RU2005102585
TH67814
US20060167042
US20080234316
UY0001027870
WO/2004/005285
ZA2004/10404
ZA200410404
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