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1. KR1020070053264 - NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE

Office Republic of Korea
Application Number 1020077006087
Application Date 16.03.2007
Publication Number 1020070053264
Publication Date 23.05.2007
Publication Kind A
IPC
C07F 9/58
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9Compounds containing elements of Groups 5 or 15 of the Periodic System
02Phosphorus compounds
547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
553having one nitrogen atom as the only ring hetero atom
576Six-membered rings
58Pyridine rings
A61K 31/66
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
CPC
C07F 9/4006
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9Compounds containing elements of Groups 5 or 15 of the Periodic System
02Phosphorus compounds
28with one or more P—C bonds
38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids ; , i.e. RP(=X)(XH)2 (X = S, Se)
40Esters thereof
4003the acid moiety containing a substituent or a structure which is considered as characteristic
4006Esters of acyclic acids which can have further substituents on alkyl
C07F 9/5728
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9Compounds containing elements of Groups 5 or 15 of the Periodic System
02Phosphorus compounds
547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
553having one nitrogen atom as the only ring hetero atom
572Five-membered rings
5728condensed with carbocyclic rings or carbocyclic ring systems
C07F 9/582
C07F 9/588
C07F 9/650964
C07F 9/650988
Applicants METABASIS THERAPEUTICS, INC.
메타베이시스 테라퓨틱스, 인크.
Inventors DANG QUN
당, 쿤
KASIBHATLA SRINIVAS RAO
카시브하트라, 스리니바스, 라오
REDDY K. RAJA
레디, 케이, 라쟈
ERION MARK D.
에리온, 마크, 디.
REDDY M RAMI
레디, 엠. 라미
AGARWAL ATUL
아가르왈, 아툴
Agents 장수길
김영
Title
(EN) NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE
(KO) 신규한 프럭토스 1,6-비스포스파타제의 헤테로방향족억제제
Abstract
(EN)

Novel FBPase inhibitors of formula (I) and (X) are useful in the treatment of diabetes and other conditions associated with elevated blood glucose.

© KIPO & WIPO 2007

(KO)
신규한 화학식 (I) 및 (X)의 FBPase 억제제는 상승된 혈액의 글루코스와 관련된 당뇨병 및 기타 질환의 치료에 유용하다.