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1. KR1020050019853 - SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ALKENYL OR ALKYNLY MOIETY FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS

Office Republic of Korea
Application Number 1020057000605
Application Date 12.01.2005
Publication Number 1020050019853
Publication Date 03.03.2005
Publication Kind A
IPC
C07D 401/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 211/96
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
92with a hetero atom directly attached to the ring nitrogen atom
96Sulfur atom
CPC
C07D 211/96
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
211Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
92with a hetero atom directly attached to the ring nitrogen atom
96Sulfur atom
C07D 239/26
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
239Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
02not condensed with other rings
24having three or more double bonds between ring members or between ring members and non-ring members
26with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C07D 401/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants ASTRAZENECA AB
아스트라제네카 아베
Inventors BURROWS JEREMY NICHOLAS
부로우스,제레미,니콜라스
TUCKER HOWARD
터커,하워드
BROWN SIMON JAMES
브라운,시몬,제임스
PATEL IAN
파텔,이안
Agents 장수길
김영
Priority Data 0216382.2 13.07.2002 GB
Title
(EN) SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ALKENYL OR ALKYNLY MOIETY FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS
(KO) 매트릭스 메탈로프로테이나제 억제제로서 유용한, 알케닐또는 알키닐 잔기를 함유하는 술포닐피페리딘 유도체
Abstract
(EN)

A compound of formula (1): wherein B is optionally substituted C2-4alkenyl or C2-4alkynyl; useful in the inhibition of one or more metalloproteinases and in particular TACE.

© KIPO & WIPO 2007

(KO)
본 발명은 1종 이상의 메탈로프로테이나제, 및 특히 TACE의 억제에 유용한 화학식 (1) (식 중, B는 임의로 치환될 수 있는 C알케닐 또는 C알키닐임)의 화합물에 관한 것이다. 2-4 2-4