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1. (KR1020090015186) PURIFICATION OF MONTELUKAST

Office : Republic of Korea
Application Number: 1020097000703 Application Date: 13.01.2009
Publication Number: 1020090015186 Publication Date: 11.02.2009
Publication Kind : A
IPC:
C07D 215/18
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
215
Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
02
having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
16
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
18
Halogen atoms or nitro radicals
CPC:
C07D 215/18
A61K 31/47
C07B 2200/13
Applicants: TEVA PHARMACEUTICAL INDUSTRIES LTD.
테바 파마슈티컬 인더스트리즈 리미티드
Inventors: STERIMBAUM GRETA
스테르임바움, 그레타
SHAPIRO EVGENY
샤피로, 에브게니
CHEN KOBI
첸, 코비
Agents: 김성기
김진회
Priority Data: 60/697,000 05.07.2005 US
Title: (EN) PURIFICATION OF MONTELUKAST
(KO) 몬테루카스트의 정제
Abstract: front page image
(EN) The present invention provides methods of purifying montelukast, a new isolated impurity of montelukast of formula I, method for its isolation, and method of using montelukast impurity as a reference marker and a reference standard. ©KIPO&WIPO 2009
(KO) 본 발명은 몬테루카스트의 정제 방법, 하기 화학식 I을 갖는 신규하게 단리된 몬테루카스트 불순물, 이의 단리 방법, 및 참조 표지물 및 참조 기준물로서 몬테루카스트 불순물을 사용하는 방법을 제공한다.
Also published as:
MXMX/a/2007/002609KR1020070088504IL185731EP1904448JP2008510840ES2358923
CN101213177CA2608369ID048.1592IN9336/DELNP/2007WO/2007/005965