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1. KR1020080106446 - IMMUNOMODULATORY AND ANTI-TUMOUR PEPTIDES

Office
Republic of Korea
Application Number 1020087023166
Application Date 23.09.2008
Publication Number 1020080106446
Publication Date 05.12.2008
Grant Number 1014562050000
Grant Date 31.10.2014
Publication Kind B1
IPC
C07K 14/435
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
C07K 14/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A61K 38/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
Applicants CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA
Inventors GUERRA VALLESPI MARIBEL
TORRENS MADRAZO ISIS DEL CARMEN
REYES ACOSTA OSVALDO
GARAY PEREZ HILDA ELISA
GUILLEN NIETO GERARDO ENRIQUE
ACEVEDO CASTRO BORIS ERNESTO
UBIETA GOMEZ RAIMUNDO
Priority Data 2006 47 24.02.2006 CU
Title
(EN) IMMUNOMODULATORY AND ANTI-TUMOUR PEPTIDES
Abstract
(EN)
The invention relates to the development of peptides originating from sequence HYRIKPTFRRLKWKKYKGKFW, into which amino acid substitutions have been introduced, which guarantee the dissociation of the lipopolysaccharide-binding capacity and potentiate the anti-tumour and immunomodulatory effect. Said peptides and combinations thereof can be used in the treatment of cancer, as well as in synergism with other standard therapies. ┬ęKIPO&WIPO 2009