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1. KR1020080019023 - PROLONGED RELEASE FORMULATION OF ACTIVE PRINCIPLES HAVING A PH-DEPENDENT SOLUBILITY

Office Republic of Korea
Application Number 1020077030484
Application Date 27.12.2007
Publication Number 1020080019023
Publication Date 29.02.2008
Publication Kind A
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
22
Sustained or differential release type
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
12
Carboxylic acids; Salts or anhydrides thereof
A61K 9/22
A61K 47/12
CPC
A61K 9/209
A61K 9/2013
A61K 9/2054
A61K 31/437
Applicants SANOFI-AVENTIS
사노피-아벤티스
Inventors ALAUX GERARD
알로, 제라르
ANDRE FREDERIC
앙드르, 프레데리크
LEWIS GARETH
루이스, 가레스
SERRE VERONIQUE
세르, 베로니크
Agents 심미성
양영준
양영환
Priority Data 0506539 28.06.2005 FR
Title
(EN) PROLONGED RELEASE FORMULATION OF ACTIVE PRINCIPLES HAVING A PH-DEPENDENT SOLUBILITY
(KO) PH-의존성 용해도를 갖는 활성 성분의 연장 방출형 제제
Abstract
(EN)
The invention concerns a novel formulation for prolonged release of an active principle having a pH-dependent solubility. The inventive formulation comprises a matrix support based on hydrophilic polymer containing a specific dose of active principle, and further comprises on or more acidifying agents in the form of an acid salt of an organic acid. ©KIPO&WIPO 2008

(KO)
본 발명은 pH-의존성 용해도를 갖는 활성 성분의 연장 방출을 위한 신규 제제에 관한 것이다. 본 발명의 제제는 특정 용량의 활성 성분을 함유하는 친수성 중합체-기재 매트릭스 지지체를 포함하고, 유기산의 산 염 형태의 1종 이상의 산성화제를 추가로 포함한다.