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1. (KR1020180091119) 암 면역요법을 위한 치료 표적으로 환자 특이적 네오에피토프의 높은 스루풋 식별 (HIGH-THROUGHPUT IDENTIFICATION OF PATIENT-SPECIFIC NEOEPITOPES AS THERAPEUTIC TARGETS FOR CANCER IMMUNOTHERAPIES)

Office : Republic of Korea
Application Number: 1020187022527 Application Date: 10.02.2017
Publication Number: 1020180091119 Publication Date: 14.08.2018
Publication Kind : A
Prior PCT appl.: Application Number: ; Publication Number:WO2017139694 Click to see the data
IPC:
G06F 19/18
A61K 35/17
A61K 39/00
A61K 39/395
A61K 48/00
C12Q 1/6881
G01N 33/569
G01N 33/574
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
10
Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
18
for functional genomics or proteomics, e.g. genotype-phenotype associations, linkage disequilibrium, population genetics, binding site identification, mutagenesis, genotyping or genome annotation, protein-protein interactions or protein-nucleic acid interactions
[IPC code unknown for A61K 35/17]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
[IPC code unknown for C12Q 1/6881]
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
569
for micro-organisms, e.g. protozoa, bacteria, viruses
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
574
for cancer
Applicants: 난토믹스, 엘엘씨
난트 홀딩스 아이피, 엘엘씨
Inventors: 윈, 앤드류
샌본, 존, 재커리
벤즈, 스티븐, 찰스
니아지, 케이반
라비자데, 샤루즈
순-시옹, 패트릭
바스케, 찰스, 죠셉
Agents: 이대호
박건홍
Priority Data: 62/294,665 12.02.2016 US
Title: (KO) 암 면역요법을 위한 치료 표적으로 환자 특이적 네오에피토프의 높은 스루풋 식별 (HIGH-THROUGHPUT IDENTIFICATION OF PATIENT-SPECIFIC NEOEPITOPES AS THERAPEUTIC TARGETS FOR CANCER IMMUNOTHERAPIES)
Abstract: front page image
(KO) 다양한 기준에 대해 필터링되는 종양 네오에피토프들의 선택을 허용하는 시스템들 및 방법들이 제시된다. 특히 고려되는 양상들에서, 필터링하는 단계는, 네오에피토프로 이어지는 돌연변이가 암 유발 유전자에 위치하는 것으로 확인되는 단계를 포함한다.
Also published as:
AU2017217877CA3014252SG11201806282XCN108701172IL261090EP3414692
US20190034582WO/2017/139694