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1. KR1020180020789 - CONJUGATE OF MINOXIDIL AND PEPTIDE

Office
Republic of Korea
Application Number 1020160105707
Application Date 19.08.2016
Publication Number 1020180020789
Publication Date 28.02.2018
Grant Number 1019482380000
Grant Date 14.02.2019
Publication Kind B1
IPC
A61K 47/48
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A61K 31/506
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
506not condensed and containing further heterocyclic rings
A61K 8/49
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
A61Q 7/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
7Preparations for affecting hair growth
C07K 19/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
19Hybrid peptides
C07K 7/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
7Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04Linear peptides containing only normal peptide links
06having 5 to 11 amino acids
Applicants (주)케어젠
CAREGEN CO., LTD.
Inventors CHUNG, YONG JI
KIM, EUN MI
정용지
김은미
Agents 특허법인태평양
Title
(EN) CONJUGATE OF MINOXIDIL AND PEPTIDE
(KO) 미녹시딜과 펩타이드의 결합체
Abstract
(EN) The present invention relates to a composition for preventing hair loss and, more specifically, to a compound having a structure in which minoxidil and a peptide are chemically connected, and to a pharmaceutical composition or cosmetic composition for preventing hair loss or promoting hair growth comprising the compound. The compound having the structure in which minoxidil and a peptide are chemically connected according to the present invention has not only excellent physiological activity such as hair loss reduction, hair growth promotion or cell growth promotion, but also excellent stability in water, thereby being useful as the composition for preventing hair loss and promoting hair growth. COPYRIGHT KIPO 2018
(KO) 본 발명은 탈모 방지용 조성물에 관한 것으로서, 보다 상세하게는 미녹시딜과 펩타이드가 화학적으로 연결된 구조를 갖는 화합물 및 이를 포함하는 탈모 방지 또는 발모 촉진용 약학적 조성물 또는 화장료 조성물에 관한 것이다. 본 발명의 미녹시딜과 펩타이드가 화학적으로 연결된 구조를 갖는 화합물은 탈모 개선, 발모 촉진, 세포 성장 촉진 등과 같은 생리활성이 우수할 뿐만 아니라 물에서의 안정성이 우수하므로, 탈모 방지 및 발모 촉진용 조성물로서 유용하게 사용될 수 있다.
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