KR1020180020789 CONJUGATE OF MINOXIDIL AND PEPTIDE

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Republic of Korea

Application Number 1020160105707

Application Date 19.08.2016

Publication Number 1020180020789

Publication Date 28.02.2018

Grant Number 1019482380000

Grant Date 14.02.2019

Publication Kind B1

IPC

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Applicants (주)케어젠
CAREGEN CO., LTD.

Inventors CHUNG, YONG JI
KIM, EUN MI
정용지
김은미

Agents 특허법인태평양

Title

(EN) CONJUGATE OF MINOXIDIL AND PEPTIDE

(KO) 미녹시딜과 펩타이드의 결합체

Abstract

(EN) The present invention relates to a composition for preventing hair loss and, more specifically, to a compound having a structure in which minoxidil and a peptide are chemically connected, and to a pharmaceutical composition or cosmetic composition for preventing hair loss or promoting hair growth comprising the compound. The compound having the structure in which minoxidil and a peptide are chemically connected according to the present invention has not only excellent physiological activity such as hair loss reduction, hair growth promotion or cell growth promotion, but also excellent stability in water, thereby being useful as the composition for preventing hair loss and promoting hair growth. COPYRIGHT KIPO 2018

(KO) 본 발명은 탈모 방지용 조성물에 관한 것으로서, 보다 상세하게는 미녹시딜과 펩타이드가 화학적으로 연결된 구조를 갖는 화합물 및 이를 포함하는 탈모 방지 또는 발모 촉진용 약학적 조성물 또는 화장료 조성물에 관한 것이다. 본 발명의 미녹시딜과 펩타이드가 화학적으로 연결된 구조를 갖는 화합물은 탈모 개선, 발모 촉진, 세포 성장 촉진 등과 같은 생리활성이 우수할 뿐만 아니라 물에서의 안정성이 우수하므로, 탈모 방지 및 발모 촉진용 조성물로서 유용하게 사용될 수 있다.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48	the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495	having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505	Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
506	not condensed and containing further heterocyclic rings

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8	Cosmetics or similar toilet preparations
18	characterised by the composition
30	containing organic compounds
49	containing heterocyclic compounds

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q	SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
7	Preparations for affecting hair growth

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
19	Hybrid peptides

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1. KR1020180020789 - CONJUGATE OF MINOXIDIL AND PEPTIDE

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
7	Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04	Linear peptides containing only normal peptide links
06	having 5 to 11 amino acids

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
7	Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04	Linear peptides containing only normal peptide links
06	having 5 to 11 amino acids

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
K	PEPTIDES
7	Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04	Linear peptides containing only normal peptide links
08	having 12 to 20 amino acids