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1. KR1020170118762 - 피롤로피리딘 화합물의 결정형

Office
Republic of Korea
Application Number 1020177023996
Application Date 26.02.2016
Publication Number 1020170118762
Publication Date 25.10.2017
Publication Kind A
IPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/437
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
437the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Applicants 제넨테크, 인크.
어레이 바이오파마 인크.
Inventors 스털츠, 제프리
린데만, 크리스토퍼 엠.
스펜서, 케이쓰 엘.
리우, 웨이동
루바치, 조셉
Agents 양영준
김영
Priority Data 62/121,396 26.02.2015 US
Title
(KO) 피롤로피리딘 화합물의 결정형
Abstract
(KO)
()-N-(4-(3-아미노피페리딘-1-일)-5-브로모-1H-피롤로[2,3-b]피리딘-3-일)사이클로프로판카복스아마이드, 및 이의 염, 용매화물 및 수화물의 결정형, 그리고 이의 약제학적 조성물, 제형 및 제조 방법이 개시된다. R