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1. (KR1020130101595) 신경보호 효과 화합물

Office : Republic of Korea
Application Number: 1020137022838 Application Date: 23.06.2006
Publication Number: 1020130101595 Publication Date: 13.09.2013
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2006024656 ; Publication Number:WO2007002512 Click to see the data
IPC:
A61K 48/00
C12N 5/071
A61K 38/18
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
CPC:
A61K 48/005
A61K 38/1875
Applicants: 티슈진, 인코포레이티드
Inventors: 이관희
이덕근
이용석
노문종
김형준
Agents: 이원희
Priority Data: 60/595,342 23.06.2005 US
Title: (KO) 신경보호 효과 화합물
Abstract: front page image
(KO) 본 출원은 a) 프로모터에 작동가능하게 연결된 형질전환 성장 인자(transforming growth factor) 슈퍼패밀리(superfamily) 또는 신경영양성 인자 단백질(neurotrophic factor protein)을 암호화하는 DNA 서열을 포함하는 재조합 바이러스 벡터 또는 플라스미드 벡터를 제조하는 단계; b) 상기 재조합 벡터를 배양된 세포의 군집에 형질감염시켜, 배양 세포의 군집을 형성시키는 단계; 및 c) 손상된 신경의 주변 영역에 상기 형질감염된 세포 군집을 이식하여, 상기 손상된 신경의 주변 영역에서 상기 DNA 서열이 발현함으로써, 신경 퇴화가 예방되는 단계를 포함하는 신경 퇴화 예방 방법을 개시한다.
Also published as:
KR1020080038310KR1020100074340EP1904113JP2009506982CN101232904CA2613551
JP2014088425KR1020140132010ES2562243KR1020160021458DK1904113CN106177996
AU2006261889AU2010257453IN10145/DELNP/2007KR1020180057737WO/2007/002512