Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (KR1020110098827) 키나제 억제제로서 유용한 카르바졸 카르복스아미드 화합물

Office : Republic of Korea
Application Number: 1020117016659 Application Date: 17.12.2009
Publication Number: 1020110098827 Publication Date: 01.09.2011
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2009068415 ; Publication Number:WO2010080481 Click to see the data
IPC:
C07D 403/06
C07D 209/88
A61K 31/496
A61P 37/00
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
403
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
209
Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
56
Ring systems containing three or more rings
80
[b, c]- or [b, d]-condensed
82
Carbazoles; Hydrogenated carbazoles
88
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496
Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
CPC:
C07D 209/88
C07D 401/04
C07D 401/12
C07D 403/04
C07D 403/10
C07D 403/12
C07D 403/14
C07D 405/12
C07D 405/14
C07D 413/10
C07D 417/04
C07D 417/10
C07D 417/12
C07D 417/14
C07D 487/04
Applicants: 브리스톨-마이어스 스큅 컴퍼니
Inventors: 류, 칭제
배트, 더글러스 쥐.
델루카, 조지 브이.
스, 칭
테븐, 앤드루 제이.
Agents: 양영준
이귀동
Priority Data: 61/139,047 19.12.2008 US
Title: (KO) 키나제 억제제로서 유용한 카르바졸 카르복스아미드 화합물
Abstract:
(KO) 본 발명은 하기 화학식 I을 갖는 화합물, 그의 거울상이성질체 및 부분입체이성질체, 제약상 허용되는 염에 관한 것이며, 화학식 I의 화합물은 Btk 조절을 비롯한 키나제 조절제로서 유용하다. <화학식 I> TIFF pct00706.tif 55 75
Also published as:
DZDZP2011000482AR074812IL213185MXMX/a/2011/006171SG171815EP2391602
JP2012512888CN102325753CA2747670EA201100992ES2443948MX2011006171
CO6390055TN2011000274BRPI0922565NZ593096AU2009335821IN4000/DELNP/2011
WO/2010/080481