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1. (KR1020110114565) 단백질 수용체 티로신 키나아제 억제제의 조성물

Office : Republic of Korea
Application Number: 1020117015933 Application Date: 08.12.2009
Publication Number: 1020110114565 Publication Date: 19.10.2011
Grant Number: 1018057540000 Grant Date: 07.12.2017
Publication Kind : B1
Prior PCT appl.: Application Number:PCTUS2009067197 ; Publication Number:WO2010077680 Click to see the data
IPC:
C07D 207/09
A61K 31/496
C07D 261/20
C07D 491/04
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
207
Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
04
having no double bonds between ring members or between ring members and non-ring members
08
with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
09
Radicals substituted by nitrogen atoms not forming part of a nitro radical
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496
Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
261
Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
20
condensed with carbocyclic rings or ring systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
CPC:
C07D 207/09
A61K 31/496
C07D 261/20
C07D 491/04
Applicants: 먼디파머 인터내셔널 코포레이션 리미티드
브이엠 파마 엘엘씨
Inventors: 우 제이 지에-창
왕 링
우 제이 지에-창
왕 링
Agents: 특허법인태평양
특허법인태평양
Priority Data: 61/120,827 08.12.2008 US
Title: (KO) 단백질 수용체 티로신 키나아제 억제제의 조성물
Abstract:
(KO) 본 발명은 수용체 티로신 키나아제 패밀리를 억제하거나 길항작용을 할 수 있는 합성 치환된 헤테로시클릭 화합물 및 이를 함유하는 약학적 조성물에 관한 것이다. 또한, 본 발명은 이러한 화합물을 통증, 암, 재협착, 동맥경화증, 건선, 혈전증, 수초형성부전 또는 탈수초화와 연관된 질병, 장애 또는 손상, 또는 NGF 수용체인 TrkA의 비정상적인 활성과 연관된 질병 또는 장애에 사용하는 용도에 관한 것이다.
Also published as:
EP2376495JP2012511054US20110301133CN102292338RU2011128013CA2746220
JP2014218524MX2011006108RU0002586212BRPI0922224JP2016180005NZ593937
AU2009333537CN106336400AU2016200153AU2017248456JP2018002741IN5183/DELNP/2011
WO/2010/077680