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1. KR1020110086768 - P2X7 조절제로서의 디히드로피리돈 아미드

Office Republic of Korea
Application Number 1020117014366
Application Date 14.12.2009
Publication Number 1020110086768
Publication Date 29.07.2011
Grant Number 1013810740000
Grant Date 11.04.2014
Publication Kind B1
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
4427
containing further heterocyclic ring systems
4439
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
04
Centrally acting analgesics, e.g. opioids
C07D 401/12
C07D 405/12
A61K 31/4439
A61P 25/04
Applicants 에프. 호프만-라 로슈 아게
Inventors 버거 제이콥
카룬 조앤 마리
크라우스 낸시 엘리자베스
로페즈-타피아 프란시스코 하비에르
워커 키스 아드리안 머레이
자오 슈-하이
Agents 특허법인코리아나
Priority Data 61/203,482 23.12.2008 US
Title
(KO) P2X7 조절제로서의 디히드로피리돈 아미드
Abstract
(KO)
하기식 I 의 화합물 또는 그 약학적으로 허용가능한 염: [식 중, m, n, R, R, R, R, R 및 R 는 본원에 정의된 바와 같음]. 또한, 화합물의 제조 방법 및 P2X7 퓨린성 수용체 관련 질환의 치료를 위한 화합물의 사용 방법이 개시되어 있다. JPEG 112011047419449-pct00036.jpg 37 66 1 2 3 4 5 a

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