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1. (JP2012511898) リボフラビンの生産方法

Office : Japan
Application Number: 2011539963 Application Date: 15.12.2009
Publication Number: 2012511898 Publication Date: 31.05.2012
Grant Number: 5813512 Grant Date: 17.11.2015
Publication Kind : B2
IPC:
C12P 19/32
C12N 1/21
C12N 15/09
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19
Preparation of compounds containing saccharide radicals
26
Preparation of nitrogen-containing carbohydrates
28
N-glycosides
30
Nucleotides
32
having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same-ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
20
Bacteria; Culture media therefor
21
modified by introduction of foreign genetic material
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
Applicants: ディーエスエム アイピー アセッツ ビー.ブイ.
Inventors: キルヒナー, フロリアン
マウフ, クラウス
シュミッド, ヨアキム
Agents: 池田 成人
山口 和弘
野田 雅一
清水 義憲
Priority Data: 102008063234.1 15.12.2008 DE
Title: (JA) リボフラビンの生産方法
Abstract:
(JA)

本発明は、リボフラビン(以下、ビタミンB2とも称する)をバイオテクノロジーにより発酵生産するための方法および手段、ならびにこの方法を実行するための手段、とりわけリボフラビン生産量が増加した修飾された微生物宿主細胞に関する。本発明はしたがって、宿主細胞のリボフラビン生産に関与する酵素活性の発現を制御するための新規な方法および手段を提供する。


Also published as:
EP2358893US20110312026CN102245781KR1020110104955IN4290/DELNP/2011WO/2010/075960