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2. (JP2010180169) CRYSTAL OF AMIDE COMPOUND

Office : Japan
Application Number: 2009025609 Application Date: 06.02.2009
Publication Number: 2010180169 Publication Date: 19.08.2010
Publication Kind : A
IPC:
C07D 413/12
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
Applicants: ASTELLAS PHARMA INC
アステラス製薬株式会社
Inventors: IKE KAZUO
池 和夫
OKAWA KAZUO
大川 和男
KONYA TORU
紺谷 徹
KAMIKAWA AKIO
神川 晃雄
Priority Data: 2009025609 06.02.2009 JP
Title: (EN) CRYSTAL OF AMIDE COMPOUND
(JA) アミド化合物の結晶
Abstract:
(EN) PROBLEM TO BE SOLVED: To provide a compound useful as an antiherpesvirus agent.

SOLUTION: New crystal form of an N-(2,6-dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl]amino}-2-oxoethyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide compound useful as an antiherpesvirus agent is found. The crystal is useful for producing a production raw material for medicines, especially a solid pharmaceutical composition.

COPYRIGHT: (C)2010,JPO&INPIT
(JA)


【課題】抗ヘルペスウイルス剤として有用な化合物を提供する。
【解決手段】抗ヘルペスウイルス剤として有用なN-(2,6-ジメチルフェニル)-N-(2-{[4-(1,2,4-オキサジアゾール-3-イル)フェニル]アミノ}-2-オキソエチル)テトラヒドロ-2H-チオピラン-4-カルボキサミド 1,1-ジオキシド化合物の新規な結晶形を見出した。
本発明の結晶は医薬の製造原体、特に固体医薬組成物の製造に有用である。
【選択図】なし