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PROBLEM TO BE SOLVED: To provide methods of treating pancreatic cancer.
SOLUTION: Provided herein are methods of treating metastatic pancreatic cancer in an individual (such as a human individual), the methods comprising administering to the individual (i) an effective amount of a composition comprising nanoparticles comprising a taxane (such as paclitaxel) and an albumin and (ii) an effective amount of gemcitabine. In some embodiments, there is provided a method of treating locally advanced unresectable pancreatic cancer in an individual (such as a human individual), the method comprising administering to the individual (i) an effective amount of a composition comprising nanoparticles comprising a taxane (such as paclitaxel) and an albumin and (ii) an effective amount of gemcitabine. In some embodiments according to (or as applied to) any of the embodiments described herein, the pancreatic cancer is pancreatic adenocarcinoma.
SELECTED DRAWING: None
COPYRIGHT: (C)2019,JPO&INPIT
【課題】膵臓がんの処置方法を提供する。【解決手段】個体(ヒト個体など)における転移性膵臓がんを処置する方法が本明細書で提供され、この方法は、(i)タキサン(パクリタキセルなど)およびアルブミンを含むナノ粒子を含む有効量の組成物;ならびに(ii)有効量のゲムシタビンを、上記個体に投与するステップを含む。一部の実施形態では、個体(ヒト個体など)における局所進行切除不能な膵臓がんを処置する方法が提供され、この方法は、(i)タキサン(パクリタキセルなど)およびアルブミンを含むナノ粒子を含む有効量の組成物;ならびに(ii)有効量のゲムシタビンを、上記個体に投与するステップを含む。本明細書に記載される実施形態のいずれかに従う(またはそれらに適用される)一部の実施形態では、この膵臓がんは膵臓腺癌である。【選択図】なし