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1. JP2019108328 - NOVEL VACCINE COMPOSITIONS COMPRISING IMMUNOSTIMULATORY OLIGONUCLEOTIDES

Office
Japan
Application Number 2019015717
Application Date 31.01.2019
Publication Number 2019108328
Publication Date 04.07.2019
Publication Kind A
IPC
A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 39/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
002Protozoa antigens
008Leishmania antigens
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
A61K 39/27
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
27Equine rhinopneumonitis virus
A61P 31/22
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
22for herpes viruses
A61P 33/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
33Antiparasitic agents
02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
CPC
A61K 39/008
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
002Protozoa antigens
008Leishmania antigens
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
A61K 39/27
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
245Herpetoviridae, e.g. herpes simplex virus
27Equine rhinopneumonitis virus
A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 2039/55561
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55561CpG containing adjuvants; Oligonucleotide containing adjuvants
A61K 2039/55566
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55566Emulsions, e.g. Freund's adjuvant, MF59
Applicants ZOETIS SERVICES LLC
ゾエティス・サービシーズ・エルエルシー
Inventors PAUL JOSEPH DOMINOWSKI
ドミノウスキー,ポール・ジョゼフ
SHARATH K RAI
ライ,シャラス・ケイ
LAUREL MARY SLY
スライ,ローレル・メアリー
COREY PATRICK COOK
クック,コーリー・パトリック
DUNCAN MWANGI
ムワンギ,ダンカン
DENNIS L FOSS
フォス,デニス・エル
KREBS RICHARD LEE
クレブス,リチャード・リー
Agents 小野 新次郎
山本 修
宮前 徹
中西 基晴
泉谷 玲子
Priority Data 61/823,189 14.05.2013 US
Title
(EN) NOVEL VACCINE COMPOSITIONS COMPRISING IMMUNOSTIMULATORY OLIGONUCLEOTIDES
(JA) 免疫刺激性オリゴヌクレオチドを含む新規のワクチン組成物
Abstract
(EN)

PROBLEM TO BE SOLVED: To provide a vaccine composition comprising an antigen component and an adjuvant component.

SOLUTION: The adjuvant component comprises a P-class immunostimulatory oligonucleotide and either a combination of a saponin and a sterol, or an oily phase comprising an oil and optionally one or more emulsifiers. The oily phase comprises 2-20 v/v% of the vaccine composition, where the antigen component is an EHV antigen or a Leishmania antigen.

SELECTED DRAWING: None

COPYRIGHT: (C)2019,JPO&INPIT


(JA)

【課題】抗原成分及びアジュバント成分を含むワクチン組成物の提供。
【解決手段】アジュバント成分は、Pクラス免疫刺激性オリゴヌクレオチド、ならびに、サポニン及びステロールの組み合わせ、または油、及び任意に、1つ以上の乳化剤を含む油相、のいずれかを含み、油相がワクチン組成物の2〜20v/v%を構成し、抗原成分が、EHV抗原またはリーシュマニア抗原である、ワクチン組成物。
【選択図】なし