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PROBLEM TO BE SOLVED: To provide a vaccine composition comprising an antigen component and an adjuvant component.
SOLUTION: The adjuvant component comprises a P-class immunostimulatory oligonucleotide and either a combination of a saponin and a sterol, or an oily phase comprising an oil and optionally one or more emulsifiers. The oily phase comprises 2-20 v/v% of the vaccine composition, where the antigen component is an EHV antigen or a Leishmania antigen.
SELECTED DRAWING: None
COPYRIGHT: (C)2019,JPO&INPIT
【課題】抗原成分及びアジュバント成分を含むワクチン組成物の提供。【解決手段】アジュバント成分は、Pクラス免疫刺激性オリゴヌクレオチド、ならびに、サポニン及びステロールの組み合わせ、または油、及び任意に、1つ以上の乳化剤を含む油相、のいずれかを含み、油相がワクチン組成物の2〜20v/v%を構成し、抗原成分が、EHV抗原またはリーシュマニア抗原である、ワクチン組成物。【選択図】なし