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1. JP2018030866 - COMPOSITION COMPRISING THEOBROMINE AND USE THEREOF IN TREATING TOOTH HYPERSENSITIVITY

Office Japan
Application Number 2017189509
Application Date 29.09.2017
Publication Number 2018030866
Publication Date 01.03.2018
Grant Number 6735260
Grant Date 15.07.2020
Publication Kind B2
IPC
A61K 31/522
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
52Purines, e.g. adenine
522having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
A23L 33/10
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
A23L 33/105
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A61K 8/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
A61K 8/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
20Halogens; Compounds thereof
A61K 8/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
24Phosphorus; Compounds thereof
CPC
A61K 6/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
20Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
A61K 6/838
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
80Preparations for artificial teeth, for filling teeth or for capping teeth
831comprising non-metallic elements or compounds thereof, e.g. carbon
838Phosphorus compounds, e.g. apatite
A61K 8/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
A61K 8/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
24Phosphorous; Compounds thereof
A61K 8/4953
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
494with more than one nitrogen as the only hetero atom
4953containing pyrimidine ring derivatives, e.g. minoxidil
A61K 31/522
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
52Purines, e.g. adenine
522having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
Applicants THEOCORP HOLDING CO LLC
テオコープ・ホールデイング・カンパニー・エルエルシー
Inventors ARMAN SADEGHPOUR
サデグプール,アルマン
NAKAMOTO TETSUO
中本 哲夫
Agents 特許業務法人小田島特許事務所
Priority Data 61/662,181 20.06.2012 US
Title
(EN) COMPOSITION COMPRISING THEOBROMINE AND USE THEREOF IN TREATING TOOTH HYPERSENSITIVITY
(JA) テオブロミンを含有する組成物および歯の知覚過敏を処置するためのそれらの使用
Abstract
(EN)

PROBLEM TO BE SOLVED: To provide a composition and method for reducing oral sensitivity, increasing the systemic health of a mammal, occluding a dentinal tubule within a mammalian tooth, and/or depositing a precipitate on the surface of a mammalian tooth.

SOLUTION: According to the present invention, there is provided an oral care composition comprising: a) isolated theobromine, or a salt or double salt thereof, or a co-crystal comprising theobromine; b) a source of calcium selected from the group consisting of calcium chloride, calcium carbonate, calcium gluconate, calcium phosphate, calcium acetate, and combinations thereof; c) a source of phosphate selected from the group consisting of potassium dihydrogen phosphate, dipotassium hydrogen phosphate, tripotassium phosphate, sodium dihydrogen phosphate, disodium hydrogen phosphate, trisodium phosphate, and combinations thereof.

SELECTED DRAWING: None

COPYRIGHT: (C)2018,JPO&INPIT

(JA)

【課題】哺乳動物の口腔感受性を下げ、全身的健康状態を上げ、哺乳動物の歯の象牙細管を閉塞し、かつ/または哺乳動物の歯の表面に沈殿物を沈着させるための組成物および方法の提供。
【解決手段】a)単離テオブロミン、またはその塩もしくは複塩、またはテオブロミンを含む共結晶;b)塩化カルシウム、炭酸カルシウム、グルコン酸カルシウム、リン酸カルシウム、酢酸カルシウム、およびそれらの組み合わせからなる群から選択されるカルシウム源;c)リン酸二水素カリウム、リン酸水素二カリウム、リン酸三カリウム、リン酸二水素ナトリウム、リン酸水素二ナトリウム、リン酸三ナトリウム、およびそれらの組み合わせからなる群から選択されるリン酸塩源;を含んでなる口腔ケア組成物。
【選択図】なし