JP2016056206 TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

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Application Number 2016005132

Application Date 14.01.2016

Publication Number 2016056206

Publication Date 21.04.2016

Grant Number 6163216

Grant Date 23.06.2017

Publication Kind B2

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Applicants UNIV DUKE
デューク　ユニバーシティ

Inventors CHEN YUAN-TSONG
チェン，ユアン－ツォン

Agents 小野　新次郎
小林　泰
竹内　茂雄
山本　修
泉谷　玲子

Priority Data 60/219,237 18.07.2000 US

Title

(EN) TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

(JA) ＩＩ型糖原病の治療

Abstract

(EN)

PROBLEM TO BE SOLVED: To provide the first effective means to treat an individual with glycogen storage disease type II.

SOLUTION: A pharmaceutical composition contains human acid α-glucosidase in a container with a label containing instructions for administration of a composition for treatment of glycogen storage disease type II.

SELECTED DRAWING: None

(JA)

【課題】II型糖原病を有する個体を治療するための最初の有効な手段を提供すること。
【解決手段】II型糖原病の治療用組成物の投与のための指示書を含むラベルを有する容器内にヒト酸α−グルコシダーゼを含有してなる医薬組成物。
【選択図】なし

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
16	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17	from animals; from humans
18	Growth factors; Growth regulators

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
08	for glucose homeostasis
10	for hyperglycaemia, e.g. antidiabetics

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9	Drugs for disorders of the cardiovascular system
02	Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38	Medicinal preparations containing peptides
16	Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17	from animals; from humans
18	Growth factors; Growth regulators

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
08	for glucose homeostasis
10	for hyperglycaemia, e.g. antidiabetics

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1. JP2016056206 - TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II

C	CHEMISTRY; METALLURGY
12	BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Y	ENZYMES
302	Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
01	Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
0102	Alpha-glucosidase (3.2.1.20)