JP2016505018 膵臓がんの処置方法

Settings

Stemming

Single Family Member

Include NPL

Feedback

Goto Application

Office

Japan

Application Number 2015552834

Application Date 10.01.2014

Publication Number 2016505018

Publication Date 18.02.2016

Grant Number 6342918

Grant Date 25.05.2018

Publication Kind B2

IPC

View less classifications

CPC

View more classifications

View less classifications

Applicants アブラクシス　バイオサイエンス，　エルエルシー

Inventors デサイ，　ニール　ピー．
レンシュラー，　マルクス

Agents 山本　秀策
森下　夏樹

Priority Data 13794480 11.03.2013 US
61/751,820 11.01.2013 US
61/752,355 14.01.2013 US

Title

(JA) 膵臓がんの処置方法

Abstract

(JA)

ゲムシタビンと組み合わせた、タキサン（パクリタキセルなど）およびキャリアタンパク質を含むナノ粒子を含む組成物の投与を含む、転移性膵臓がんの処置のための方法が、本明細書に提供される。ヒト個体における転移性または局所進行膵臓がんを処置する方法であって、（ａ）パクリタキセルおよびアルブミンを含むナノ粒子を含む有効量の組成物；ならびに（ｂ）有効量のゲムシタビンを該個体に投与するステップを含み、該個体が、（ｉ）肝臓に転移を有すること、（ｉｉ）３つ以上の転移部位を有すること、（ｉｉｉ）膵臓の頭部の原発位置に膵臓がんを有すること、および／または（ｉｖ）≧５９×ＵＬＮ（正常の上限）である血清ＣＡ１９−９レベルを有することに基づいて処置のために選択される、方法。

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
7042	Compounds having saccharide radicals and heterocyclic rings
7052	having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706	containing six-membered rings with nitrogen as a ring hetero atom
7064	containing condensed or non-condensed pyrimidines
7068	having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
335	having oxygen as the only ring hetero atom, e.g. fungichromin
337	having four-membered rings, e.g. taxol

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30	Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
42	Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1	Drugs for disorders of the alimentary tract or the digestive system
18	for pancreatic disorders, e.g. pancreatic enzymes

Processing

National Phase Entries

Authority File

Settings

Feedback

Goto Application

1. JP2016505018 - 膵臓がんの処置方法

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
50	Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51	Nanocapsules; Nanoparticles;
5107	Excipients; Inactive ingredients
513	Organic macromolecular compounds; Dendrimers
5169	Proteins, e.g. albumin, gelatin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
48	Preparations in capsules, e.g. of gelatin, of chocolate
50	Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51	Nanocapsules; Nanoparticles;
5107	Excipients; Inactive ingredients
513	Organic macromolecular compounds; Dendrimers
5169	Proteins, e.g. albumin, gelatin