JP2015535256 ピラゾロピリダジンならびに網膜変性疾患およびアッシャー症候群に伴う聴力損失を処置するための方法

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Single Family Member

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Office

Japan

Application Number 2015539867

Application Date 25.10.2013

Publication Number 2015535256

Publication Date 10.12.2015

Grant Number 6290910

Grant Date 16.02.2018

Publication Kind B2

IPC

CPC

Applicants アッシャー・サード・イニシアティブ・インコーポレイテッド

Inventors ブーリ，ローランド・ワーナー
エスミュ，ウィリアム・ラメシュチャンドラ・クリシュナ
ロック，クリストファー・ジェームズ
マラグ，カリネ・ファビエンヌ
オーエンズ，アンドリュー・ペイト
ハート，ウィリアム・エドワード

Agents 特許業務法人川口國際特許事務所

Priority Data 61/718,593 25.10.2012 US
61/775,376 08.03.2013 US

Title

(JA) ピラゾロピリダジンならびに網膜変性疾患およびアッシャー症候群に伴う聴力損失を処置するための方法

Abstract

(JA)

網膜色素変性、レーバー先天黒内障、症候性網膜変性、加齢性黄斑変性およびアッシャー症候群などの網膜変性疾患、ならびにアッシャー症候群に伴う聴力損失の処置のための化合物、組成物および方法が本明細書で開示される。

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
487	Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02	in which the condensed system contains two hetero rings
04	Ortho-condensed systems

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495	having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50	Pyridazines; Hydrogenated pyridazines
5025	ortho- or peri-condensed with heterocyclic ring systems

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535	having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
5375	1,4-Oxazines, e.g. morpholine
5377	not condensed and containing further heterocyclic rings, e.g. timolol

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27	Drugs for disorders of the senses
02	Ophthalmic agents

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27	Drugs for disorders of the senses
16	Otologicals