JP2015509102 三環式スルホン化合物並びにその作製および使用方法

Settings

Stemming

Single Family Member

Include NPL

Office

Japan

Application Number 2014553404

Application Date 17.01.2013

Publication Number 2015509102

Publication Date 26.03.2015

Publication Kind A5

IPC

CPC

Applicants ザフゲン，インコーポレイテッド

Inventors ペリン，トーマス　デビッド
ダイク，ヘイゼル　ジョーン
クランプ，スーザン　メアリー
ザーラー，ロバート

Agents 新樹グローバル・アイピー特許業務法人

Priority Data 61/587,825 18.01.2012 US

Title

(JA) 三環式スルホン化合物並びにその作製および使用方法

Abstract

(JA)

本発明は、三環式スルホン化合物、肥満等の医的障害を治療する場合のその使用を提供する。医薬組成物および様々な三環式化合物を作製する方法を提供する。化合物はメチオニルアミノペプチダーゼ２に対する活性を有すると解釈されている。

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
311	Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
02	ortho- or peri-condensed with carbocyclic rings or ring systems
78	Ring systems having three or more relevant rings

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
095	Sulfur, selenium or tellurium compounds, e.g. thiols
10	Sulfides; Sulfoxides; Sulfones

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
335	having oxygen as the only ring hetero atom, e.g. fungichromin
35	having six-membered rings with one oxygen as the only ring hetero atom
352	condensed with carbocyclic rings, e.g. cannabinols, methantheline

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435	having six-membered rings with one nitrogen as the only ring hetero atom
47	Quinolines; Isoquinolines
473	ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
04	Anorexiants; Antiobesity agents

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
C	ACYCLIC OR CARBOCYCLIC COMPOUNDS
317	Sulfones; Sulfoxides
44	having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton