JPWO2013122135 経口用医薬組成物

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Application Number 2013558723

Application Date 14.02.2013

Publication Number WO2013122135

Publication Date 22.08.2013

Grant Number 5798642

Grant Date 28.08.2015

Publication Kind B2

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Applicants 大鵬薬品工業株式会社

Inventors 大西　敬人
尾形　哲夫

Agents 特許業務法人アルガ特許事務所
高野　登志雄
中嶋　俊夫
村田　正樹
山本　博人

Priority Data 2012031144 15.02.2012 JP

Title

(JA) 経口用医薬組成物

Abstract

(JA)

高湿度条件下でも安定であり経口投与可能なＦＴＤ及びＴＰＩ含有経口用医薬組成物を提供する。
α，α，α−トリフルオロチミジン及び５−クロロ−６−（２−イミノピロリジン−１−イル）メチル−２，４（１Ｈ，３Ｈ）−ピリミジンジオン塩酸塩を有効成分として含み、金属塩からなる添加剤を実質的に含有しない経口用医薬組成物。

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
7042	Compounds having saccharide radicals and heterocyclic rings
7052	having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706	containing six-membered rings with nitrogen as a ring hetero atom
7064	containing condensed or non-condensed pyrimidines
7068	having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
7072	having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
20	Pills, lozenges or tablets

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
20	Pills, lozenges or tablets
28	Dragees; Coated pills or tablets

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495	having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505	Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
513	having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47	Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06	Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08	containing oxygen
10	Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols ; Poloxamers; PEG/POE alkyl ethers

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1. JPWO2013122135 - 経口用医薬組成物

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35	Antineoplastic agents

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9	Medicinal preparations characterised by special physical form
14	Particulate form, e.g. powders, ; Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
16	Agglomerates; Granulates; Microbeadlets ; ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
1605	Excipients; Inactive ingredients
1617	Organic compounds, e.g. phospholipids, fats
1623	Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules