Processing

Please wait...

PATENTSCOPE will be unavailable a few hours for maintenance reason on Tuesday 27.07.2021 at 12:00 PM CEST
Settings

Settings

Goto Application

1. JP2014210747 - ORAL VACCINE HAVING IMPROVED CELL-MEDIATED IMMUNITY INDUCTION POTENCY

Office
Japan
Application Number 2013088800
Application Date 19.04.2013
Publication Number 2014210747
Publication Date 13.11.2014
Publication Kind A
IPC
A61K 39/07
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
07Bacillus
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
CPC
A61K 35/747
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
741Probiotics
744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
747Lactobacilli, e.g. L. acidophilus or L. brevis
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
A61K 2039/521
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
52Bacterial cells; Fungal cells; Protozoal cells
521inactivated (killed)
A61K 2039/523
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
52Bacterial cells; Fungal cells; Protozoal cells
523expressing foreign proteins
A61K 2039/542
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
54characterised by the route of administration
541Mucosal route
542oral/gastrointestinal
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
Applicants ANGES MG INC
アンジェス株式会社
BIOLEADERS CORP
バイオリーダーズ コーポレーション
Inventors NOMURA EIJI
野村 栄司
TENMAN AKIKO
天満 昭子
NAKAZAWA TAKAHIRO
中澤 隆弘
MORISHITA RYUICHI
森下 竜一
Agents 高島 一
土井 京子
鎌田 光宜
田村 弥栄子
山本 健二
村田 美由紀
小池 順造
當麻 博文
Title
(EN) ORAL VACCINE HAVING IMPROVED CELL-MEDIATED IMMUNITY INDUCTION POTENCY
(JA) 細胞性免疫誘導能が改善された経口ワクチン
Abstract
(EN)

PROBLEM TO BE SOLVED: To provide a pharmaceutical technique which reduces an effective dosage amount of an oral vaccine containing as an active ingredient killed lactic acid bacteria which express a target antigen on the surface.

SOLUTION: Provided is an oral formulation for prevention or treatment of the pathogen infectious disease, containing killed lactic acid bacteria which express a pathogenic antigen on the surface with a mean particle diameter of 2.68-30 μm, or an atomized material thereof. Provided is an oral formulation for inducing cell-mediated immunity against the target antigen concerned, containing the killed lactic acid bacteria which express the target antigen on the surface with a particle diameter of 2.68-30 μm, or an atomized material thereof.

COPYRIGHT: (C)2015,JPO&INPIT

(JA)

【課題】標的抗原を表面発現する死菌化乳酸菌を有効成分とする経口ワクチンの有効投与量を低減させる製剤技術を提供すること。
【解決手段】平均粒子径2.68〜30μmの、病原体抗原を表面発現する死菌化乳酸菌又はその微粒化物を含む、当該病原体感染性疾患の予防又は治療のための経口製剤。粒子径2.68〜30μmの、標的抗原を表面発現する死菌化乳酸菌又はその微粒化物を含む、当該標的抗原に対する細胞性免疫を誘導するための経口製剤。
【選択図】なし