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1. JP2011144201 - INTERFERON- FOR ANTI-VIRUS THERAPY FOR RESPIRATORY DISEASE

Office Japan
Application Number 2011093677
Application Date 20.04.2011
Publication Number 2011144201
Publication Date 28.07.2011
Publication Kind A5
IPC
A61K 38/21
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
19Cytokines; Lymphokines; Interferons
21Interferons
A61K 31/7088
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
CPC
A61K 31/56
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
A61K 31/7088
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
A61K 38/215
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
19Cytokines; Lymphokines; Interferons
21Interferons ; [IFN]
215IFN-beta
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 37/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
02Immunomodulators
04Immunostimulants
Applicants UNIV OF SOUTHAMPTON
ユニバーシティ、オブ、サウサンプトン
Inventors DAVIES DONNA ELIZABETH
デビース,ドナ,エリザベス
WARK PETER ALEXANDER BLANCH
ウォーク,ピーター,アレクサンダー,ブランチ
HOLGATE STEPHEN
ホルゲート,スティーブン
JOHNSTON SEBASTIAN L
ジョンストン,セバスチャン,エル
Agents 平木 祐輔
石井 貞次
藤田 節
Priority Data 0405634.7 12.03.2004 GB
Title
(EN) INTERFERON- FOR ANTI-VIRUS THERAPY FOR RESPIRATORY DISEASE
(JA) 呼吸器疾患の抗ウイルス療法のためのインターフェロン-β
Abstract
(EN)

PROBLEM TO BE SOLVED: To provide a medicine for treatment of rhinovirus-induced exacerbation of a respiratory disease selected from asthma and chronic obstructive pulmonary diseases.

SOLUTION: An agent (a) that increases endogenous interferon- (IFN-) expression in the lung or a polynucleotide (b) that can express the agent (a) is used in the production of the medicine for treatment of rhinovirus-induced exacerbation of a respiratory disease selected from asthma and chronic obstructive pulmonary diseases (COPD), wherein the treatment is performed by airway delivery of the medicine.

COPYRIGHT: (C)2011,JPO&INPIT

(JA)

【課題】 喘息および慢性閉塞性肺疾患から選択される呼吸器疾患のライノウイルスが誘発する増悪を治療するための医薬を提供する。
【解決手段】 喘息及び慢性閉塞性肺疾患(COPD)から選択される呼吸器疾患のライノウイルスが誘発する増悪を治療するための医薬の製造における、(a)肺において内在性インターフェロンβ(IFN-β)の発現を増加させる薬剤、又は(b)(a)の薬剤を発現できるポリヌクレオチドの使用であって、前記治療は前記医薬の気道送達によりなされるものである、前記使用。
【選択図】 なし