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1. JP2005132845 - ANALOGUE OF GLP-1

Office Japan
Application Number 2004363831
Application Date 16.12.2004
Publication Number 2005132845
Publication Date 26.05.2005
Grant Number 4620444
Grant Date 05.11.2010
Publication Kind B2
IPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C07K 14/605
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
605Glucagons
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 3/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
A61P 3/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
Applicants SOC DE CONSEILS DE RECHERCHES & D'APPLICATIONS SCIENTIFIQUES SAS
ソシエテ ド コンセイユ ド ルシェルシェ エ ダアップリカーション シャンティフィック (エス.セー.エール.アー.エス.)
Inventors DONG ZHENG XIN
ドン,ツェン・シン
Agents 社本 一夫
今井 庄亮
増井 忠弐
小林 泰
富田 博行
江尻 ひろ子
Priority Data 09/206,601 07.12.1998 US
60/111,255 07.12.1998 US
Title
(EN) ANALOGUE OF GLP-1
(JA) GLP-1の類似体
Abstract
(EN)

PROBLEM TO BE SOLVED: To obtain a pharmaceutical composition for treating diseases such as diabetes and a respiratory tract secretion disease and containing an analogue of amide of glucagon-like peptide-1 (GLP-1).

SOLUTION: The pharmaceutical composition comprises an effective amount of a compound of the peptide analogue of the glucagon-like peptide-1, having the formula (Aib8,35)hGLP-1(7-36)NH2 or a pharmaceutically permissible salts thereof, and a pharmaceutically permissible vehicle or a diluent thereof. Use of the compound in production of pharmaceuticals for treating the disease is provided.

COPYRIGHT: (C)2005,JPO&NCIPI

(JA)

【課題】糖尿病、気道の分泌障害等の疾患を治療するためのグルカゴン様ペプチド−1のアミド(GLP−1)の類似体を含有する医薬組成物。
【解決手段】グルカゴン様ペプチド−1のペプチド類似体である以下の式:(Aib8,35)hGLP−1(7−36)NH2の化合物又はその製剤的に許容される塩の有効量と製剤的に許容される担体又は希釈剤を含んでなる医薬組成物、及び疾患治療用医薬品の製造における上記式の化合物の使用。
【選択図】なし