JP2005500288 ＦＬＡＶＩＶＩＲＵＳ感染の治療または予防のための化合物および方法

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Japan

Application Number 2003503618

Application Date 11.06.2002

Publication Number 2005500288

Publication Date 06.01.2005

Grant Number 4544857

Grant Date 09.07.2010

Publication Kind B2

IPC

CPC

Applicants ヴァイロケム　ファーマ　インコーポレイテッド

Inventors チャン，チュン，コン，ラバル
ベダード，ジーン
ダス，サンジョイ，クマール
ヌエン　バ，ネ
ペレイラ，オズウィー，ゼット．
レディー，トゥムクンタ，ジャガディーズウォー
シディキ，エム．，アルシャッド
ワン，ウーイ
ヤンノパウロス，コンスタンチン

Agents 細田　芳徳

Priority Data 60/296,731 11.06.2001 US

Title

(JA) ＦＬＡＶＩＶＩＲＵＳ感染の治療または予防のための化合物および方法

Abstract

(JA)

本発明は、flaviviridaeウイルス感染を治療するのに有用な式Iによって表わされる新規な化合物またはその薬学的に許容される塩を提供する。

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
D	HETEROCYCLIC COMPOUNDS
333	Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
02	not condensed with other rings
04	not substituted on the ring sulfur atom
26	with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
38	Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
40	Thiophene-2-carboxylic acid

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
38	having sulfur as a ring hetero atom
381	having five-membered rings

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
38	having sulfur as a ring hetero atom
382	having six-membered rings, e.g. thioxanthenes

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40	having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
4025	not condensed and containing further heterocyclic rings, e.g. cromakalim

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
33	Heterocyclic compounds
395	having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40	having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403	condensed with carbocyclic rings, e.g. carbazole
4035	Isoindoles, e.g. phthalimide

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1	Drugs for disorders of the alimentary tract or the digestive system
16	for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

C	CHEMISTRY; METALLURGY
07	ORGANIC CHEMISTRY
F	ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
7	Compounds containing elements of Groups 4 or 14 of the Periodic System
02	Silicon compounds
08	Compounds having one or more C-Si linkages
10	containing nitrogen