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1. (JPWO2017099238) 癌の治療及び/又は予防用医薬組成物

Office : Japan
Application Number: 2016574015 Application Date: 09.12.2016
Publication Number: WO2017099238 Publication Date: 15.06.2017
Publication Kind : A1
IPC:
A61K 31/7088
A61K 35/76
A61P 43/00
A61K 48/00
A61K 45/00
A61K 47/50
A61K 31/7105
C12N 15/113
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
76
Viruses
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
[IPC code unknown for A61K 47/50]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
7105
Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
113
Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
Applicants: 東レ株式会社
Inventors: 宮野 敦子
須藤 裕子
高山 愛子
荒井 大河
Agents: 平木 祐輔
藤田 節
小瀬村 暁子
Priority Data: 2015240951 10.12.2015 JP
Title: (JA) 癌の治療及び/又は予防用医薬組成物
Abstract:
(JA)

本発明は、癌と関連する様々なmiRNAを由来とするポリヌクレオチドを有効成分とする新たな癌の治療及び/又は予防用医薬組成物、この医薬組成物と別の抗腫瘍剤との組み合わせ医薬品、並びに、これらの医薬組成物又は組み合わせ医薬品を用いて癌をもつ被検体を治療又は予防する方法を提供する。本発明は、配列番号1又は2で表される塩基配列を含むポリヌクレオチドを有効成分として含む、癌の治療及び/又は予防用医薬組成物(但し前記ポリヌクレオチドの少なくとも一部がDNAである場合、前記塩基配列中のDNAに相当する領域のウラシルはチミンに読み替える)に関する。


Also published as:
EP3388067US20180362981WO/2017/099238