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1. (IN201827033800) METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR

Office : India
Application Number: 201827033800 Application Date: 07.09.2018
Publication Number: 201827033800 Publication Date: 11.01.2019
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2016052346 ; Publication Number:PCTUS2016052346 Click to see the data
IPC:
C12N 15/87C
[IPC code unknown for ERROR IPC Code incorrect: invalid subgroup (0=>999999)!]
Applicants: CIBUS US LLC
CIBUS EUROPE B.V.
Inventors: BEETHAM, Peter, R.
GOCAL, Gregory, F.W.
SCHOPKE, Christian
SAUER, Noel
PEARCE, James
SEGAMI, Rosa, E.
MOZORUK, Jerry
Priority Data: 62/293278 09.02.2016 US
Title: (EN) METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
Abstract:
(EN) Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments methods and compositions for modifying a DNA sequence in a cell (such as a plant bacterial yeast fungal algal or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms such as a DNA cutter.
Also published as:
CA3014036KR1020180116769CN109072248BR112018016278EA201891629WO/2017/138986