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1. (IN201817024262) MICROBIAL STRAIN IMPROVEMENT BY A HTP GENOMIC ENGINEERING PLATFORM

Application Number: 201817024262 Application Date: 29.06.2018
Publication Number: 201817024262 Publication Date: 30.11.2018
Publication Kind : A
Prior PCT appl.: Application Number:PCTUS2016065465 ; Publication Number: Click to see the data
IPC:
G06F 19/22G
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Applicants: ZYMERGEN INC.
Inventors: SERBER, Zach
DEAN, Erik Jedediah
MANCHESTER, Shawn
GORA, Katherine
FLASHMAN, Michael
SHELLMAN, Erin
KIMBALL, Aaron
SZYJKA, Shawn
FREWEN, Barbara
TREYNOR, Thomas
BRUNO, Kenneth S.
Priority Data: 15/140296 27.04.2016 US
62/264232 07.12.2015 US
62/368786 29.07.2016 US
Title: (EN) MICROBIAL STRAIN IMPROVEMENT BY A HTP GENOMIC ENGINEERING PLATFORM
Abstract:
(EN) The present disclosure provides a HTP microbial genomic engineering platform that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition. The HTP genomic engineering platform described herein is microbial strain host agnostic and therefore can be implemented across taxa. Furthermore, the disclosed platform can be implemented to modulate or improve any microbial host parameter of interest.