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1. IN201817024262 - MICROBIAL STRAIN IMPROVEMENT BY A HTP GENOMIC ENGINEERING PLATFORM

Office India
Application Number 201817024262
Application Date 29.06.2018
Publication Number 201817024262
Publication Date 30.11.2018
Publication Kind A
IPC
G06F 19/22
GPHYSICS
06COMPUTING; CALCULATING OR COUNTING
FELECTRIC DIGITAL DATA PROCESSING
19Digital computing or data processing equipment or methods, specially adapted for specific applications
10Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
22for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or Single-Nucleotide Polymorphism discovery or sequence alignment
Applicants ZYMERGEN INC.
Inventors SERBER, Zach
DEAN, Erik Jedediah
MANCHESTER, Shawn
GORA, Katherine
FLASHMAN, Michael
SHELLMAN, Erin
KIMBALL, Aaron
SZYJKA, Shawn
FREWEN, Barbara
TREYNOR, Thomas
BRUNO, Kenneth S.
Priority Data 15140296 27.04.2016 US
62/264232 07.12.2015 US
62/368786 29.07.2016 US
Title
(EN) MICROBIAL STRAIN IMPROVEMENT BY A HTP GENOMIC ENGINEERING PLATFORM
Abstract
(EN)
The present disclosure provides a HTP microbial genomic engineering platform that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition. The HTP genomic engineering platform described herein is microbial strain host agnostic and therefore can be implemented across taxa. Furthermore, the disclosed platform can be implemented to modulate or improve any microbial host parameter of interest.